Most of the evidence for the effectiveness of lipotropic injections is based on the research behind individual components rather than the combined formula
Vegans, vegetarians, people over the age 50, anyone with stomach/bowel issues like chronic gastritis, leaky gut, IBS or celiac, and anyone who regularly takes medications such as Metformin, PPIs (used for GERD), H2 Receptor Antagonists (used for peptic ulcers), or anything that interferes with stomach acid production are actually at risk for vitamin B12 deficiency, and should supplement B12 regularly
[PMID: 17042787] PubMed record related to this compound for laboratory literature review
For shots, a common first dose is 1000 mcg daily for a week
Faster Results Most patients feel effects within 3060 minutes, versus hours or days with oral supplements