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The goal of a GLP-1 is sustainable weight loss and the improvement of overall metabolic health, including blood sugar, blood pressure, and cholesterol
Morphine also inhibits NLRP3 inflammasomes in macrophages ( via -opioid receptors on immune cells) in some studies (131)
For most patients, I recommend starting with weekly sessions for 4-6 weeks
However, as a precaution, tirzepatide is contraindicated in individuals with a personal or family history of MTC or multiple endocrine neoplasia syndrome type 2 (MEN 2)
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