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Darkened alveolar bone with minocycline therapy (10% at 1 year, 20% at 4 years of therapy) Diagnosis History of exposure to, or ingestion of, heavy metals or drugs Differentiation from melanocyte-related pigmentation by biopsy if necessary Differential Diagnosis When localized: amalgam tattoo, mucosal melanotic macule, melanoacanthoma, mucosal nevus, ephelides, Kaposis sarcoma, purpura, malignant melanoma, ecchymosis When generalized: ethnic pigmentation, Addisons disease If asymmetric, in situ melanoma must be ruled out by biopsy

Add a daily brisk walk of about one hour in length to preserve muscle mass, suggests preliminary evidence

There are two common and effective approaches our team recommends

Board Certified Primary Care Physician Dr

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