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The SYNCHRONIZE-1 trial evaluated survodutides safety and efficacy in adults with overweight or obesity, excluding those with type 2 diabetes
Current guidelines suggest at least 150 minutes of moderate aerobic activity per week plus strength training twice weekly
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This program runs through December 31, 2027
In addition, liraglutide is a short-acting GLP-1 agonist, with subcutaneous dose of 1.25-1.9 mg per day, based on the pharmacokinetics results in rabbit, the inventors concluded that the drug concentration up to 50 mg/mL have to be used, with 2-4 doses per day, the frequent nasal dosing will potentially result in toxic effects, as well as poor patient compliance
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