glp 1 lizard spit Gila monster venom… and weight loss? 🦎 It sounds wild, but it's true. GLP-1 medications were inspired by a hormone first discovered in the saliva of a Gila monster. On this week's Semaglutide (Ozempic): From Lizard Spit

Lancet 1987;2:1300-4.ArticlePubMed 5

In Conclusion Until there is more evidence-based research on the impact of GLC-1 receptor agonists on anesthesia, specifically conscious sedation, DOCS Education recommends a medical consult with the patients PCP or endocrinologist, and absent the strong recommendation to the contrary from their prescribing physician, have the patient withhold their weekly injectable GLP-1 receptor antagonist one week before sedation, and their daily GLP-1 receptor agonist on the day of the sedation appointment, and be NPO 6 hours before the appointment as usual

Key methods include: 2.4

The marketing claims have not been independently verified or evaluated by the FDA

Additionally, these medications require strict refrigeration to maintain their effectiveness, and improper storage can render them useless or worse, unsafe