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Nassini R, Gees M, Harrison S, et al
Several pharmaceutical companies are actively pursuing GLP-1 based therapies for alcohol use disorder (AUD), signalling a growing interest in expanding their use beyond metabolic conditions
[1] [9] This is clinically important because medicines that inhibit CYP2C19 such as omeprazole, esomeprazole, and cimetidine can increase escitalopram plasma concentrations, potentially raising the risk of side effects including QT interval prolongation
The mechanisms behind them
Brand-name tirzepatide (Zepbound, Mounjaro) is FDA-approved, meaning its purity, potency, and safety are rigorously tested and standardized
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