Here's what we'll cover Here's what we'll cover Here's what we'll cover Key takeaways Semaglutide is the active ingredient in Ozempic and Wegovy, and has been proven to help people lose weight in combination with lifestyle changes like diet and exercise

Typically mild and improves over 1-2 weeks at each dose level Constipation : Tirzepatide slows gastric emptying, which can reduce bowel movement frequency Diarrhea : Some patients experience the opposite problem, particularly at higher doses Headaches : Common in the first week or two, usually resolving on their own Fatigue : Especially during early treatment when caloric intake drops significantly Injection site reactions : Redness, itching, or mild swelling at the injection site Dry mouth : A less discussed but fairly common side effect Muscle pain : Some patients report muscle aches, particularly during dose escalation Anxiety : Less common but reported by some patients VitaStir reviewers consistently mention that side effects are manageable
N Engl J Med 2013;369:1327-1335
These options can be more reliable if you are using semaglutide and have ongoing stomach side effects
de Souza Marinho T, Martins FF, de Macedo Cardoso LE, Aguila B, Mandarim-de-Lacerda CA