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60% of participants achieved 20% or more weight loss -- a threshold historically associated with bariatric surgery outcomes
The daily oral dosing schedule creates a different side effect pattern than weekly injectables, with potentially more consistent but possibly less intense daily GI exposure
The initial dosages are gradually increased to minimize side effects and allow the patients body to adjust to the medication
Palavras MA, Kaio GH, de Mari J, Claudino AM (May 2011) A review of latin American studies on binge-eating disorder
Future studies are needed to explore the interneural communication networks in key regions of the brain and signal transduction pathways through which GIPR antagonism recruits GLP-1R signalling
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