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However, they may improve obesity-related risk factors such as excess body weight, systemic inflammation, and insulin resistance.

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Bibcode:2015Sci...348...62R

Common risk factors include structural predispositions, such as a crowded optic disc and optic disc drusen (ODD), and systemic conditions like sleep apnea syndrome, hypertension, hyperlipidemia, nocturnal hypotension, diabetes mellitus, and hypercoagulability [1, 2]