GLP-1 receptor agonists may be considered when additional treatment goals include weight reduction, improved glycemic control, chronic kidney disease risk reduction, or lowering atherosclerotic cardiovascular risk, particularly in patients with obesity or established Atherosclerotic Cardiovascular Disease (ASCVD) [7, 16, 47]
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Weight Loss: The Default Job The pivotal obesity trial enrolled about 1,960 non-diabetic adults with a mean weight of 105 kg, BMI of 38, average age of 46, and a cohort that was roughly three-quarters women
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Unlike intravenous administrationwhere air bubbles could theoretically enter the bloodstream and cause complicationssubcutaneous injections deliver medication into the fatty tissue layer beneath the skin, where small air bubbles are harmlessly absorbed by the body