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Each injection should contain at least 5,000 mcg of pharmaceutical-grade methylcobalamin to be effective, and most patients notice improvements in energy, sleep, and mood within weeks of starting proper B12 therapy
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When it comes to supplements, taking high doses of vitamin C at the same time as your B12 shot might slightly lower the amount of B12 your body can use, but this is more relevant for oral B12 supplements than injections
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