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However, weight loss without muscle preservation can result in the loss of both fat and lean body mass (muscle) especially if the individual is not consuming enough protein or doing resistance training

(1997, Journal of Endocrinology) reported that IGF-1 LR3 supported protein turnover in tumor-bearing catabolic rats but also increased tumor growth in that model

Supplementary information Supplementary Methods, Figs

Sam West, author on the study and postdoctoral researcher at the University of Oxford, said: People taking medication lose more weight compared with behaviour programmes, but they regain the weight four times faster. In the paper, the team questioned the cost-effectiveness to the NHS of drug treatment