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Critical Research Limitations These findings, while encouraging, come with significant caveats: Very small sample sizes (typically fewer than 10 mother-infant pairs) Short observation periods (no multi-year developmental follow-up) No data on younger infants (most studies involved babies over 4 months old) Unknown long-term effects on infant metabolism, pancreatic function, or growth patterns As the National Institutes of Health's LactMed database notes, while semaglutide was not detectable in milk samples, "the long-term effects of infant exposure are unknown." Beyond Direct Transfer: Indirect Effects on Breastfeeding Even if Ozempic doesn't transfer significantly into breast milk, it can affect breastfeeding through other mechanisms that are particularly important for Australian mothers to understand

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