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The effectiveness of peptides can vary based on their composition, dosage, and method of administration

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This assessment is supported by a report of a prefusion-stabilized version of the HCMV gB ectodomain used to immunize mice: notably, the stabilized construct did not produce superior neutralization titres compared with a non-stabilized postfusion construct, whereas general complement-independent elicitation of neutralizing antibodies was low 17