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Small molecule dipeptidylpeptidase IV inhibitors under investigation for diabetes mellitus therapy
2 Side effects and tolerability Both medications share similar gastrointestinal side effects
Aronne, MD, an obesity specialist at Weill Cornell Medicine in New York City
Decrease food intake Enhances insulin secretion Improves insulin sensitivity Additional actions include delayed gastric emptying* and reduced glucagon levels *This effect diminishes over time
Arterial blood gas (ABG) analysis showed severe mixed respiratory and metabolic acidosis (pH 7.17, PCO 2 68.5 mmHg, PO 2 28.2 mmHg, HCO 3 18.8 mmol/L)
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