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Its broad range of biological activities has made it an important research compound across multiple fields, including tissue regeneration, gastrointestinal biology, vascular development, and connective tissue science
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doi: 10.1172/JCI143777 61 HeM.WeiW.ZhangY.XiangZ.PengD.KasimumaliA.et al
Lancet 383(9911):3139 Tabernero J et al (2015) Ramucirumab versus placebo in combination with second-line FOLFIRI in patients with metastatic colorectal carcinoma that progressed during or after first-line therapy with bevacizumab, oxaliplatin, and a fluoropyrimidine (RAISE): a randomised, double-blind, multicentre, phase 3 study
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