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NSAIDs NSAIDs inhibit cyclooxygenase enzymes, reducing prostaglandin synthesis and thereby inflammation and pain
It typically presents as macrocytic megaloblastic anemia and neurological impairments, including sensory and motor disfunctions, predominantly in the lower extremities, ataxia, and in more advanced stages cognitive decline progressing to dementia, as well as psychiatric disturbances (Sanjay et al., 2022
The compounds effects on fat metabolism are particularly noteworthy
The loss of this single protein has cascading effects
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