al., Sympathetic Neurotransmitter, VIP, Delays Intervertebral Disc Degeneration via FGF18/FGFR2-Mediated Activation of Akt Signaling Pathway, Advanced Biology (2023)
doi: 10.3389/fnut.2025.1598588 Received 23 March 2025 Accepted 08 May 2025 Published 30 May 2025 Volume 12 - 2025 Edited by Jing Gao, National Engineering Research Center for Oil Tea, China Reviewed by Tarique Hussain, Nuclear Institute for Agriculture and Biology, Pakistan Guiping Guan, Hunan Agricultural University, China Updates Copyright 2025 Li, Li and Fan
MR analysis indicated that genetically proxied GLP-1RAs were associated with a reduced risk of AF (odds ratio [OR] = 0.78, 95% confidence interval [CI] = 0.710.85, p = 4.45E-08, posterior probability of hypothesis 4 [PP.H4] = 0.007) and a lower risk of cardiac arrest and ventricular fibrillation (OR = 0.60, 95% CI = 0.420.85, p = 0.0039, PP.H4 = 0.018)
Many people report no immediate effects at all, especially at lower doses
Human data is extremely limited