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doi: 10.1007/s12602-024-10364-7 277 GurruchagaHSaenz del BurgoLCirizaJOriveGHernndezRMPedrazJL

Proton-pump inhibitors (e.g., omeprazole, esomeprazole, and lansoprazole), used to treat Zollinger-Ellison syndrome and gastroesophageal reflux disease (GERD), markedly decrease stomach acid secretion required for the release of vitamin B 12 from food but not from supplements

This dual activity at related receptor systems is part of what distinguishes cagrilintide from selective amylin-only analogs

56 The significant decrease in distensibility from the cushioning aorta to conducting vessels such as muscular arteries leads to an impedance change promoting wave reflection and pulse pressure elevation

(PubMed) Arai H, Kono N