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Abstract In the mouth, melanin is produced by melanocytes residing in the basal cell layer of the oral epithelium
Regulatory Status and Quality Concerns The FDA has not approved either AOD-9604 or MOTS-c for any indication
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However, berberine has also been shown to have some weight loss effects, and it has fewer potential side effects, making it an appealing natural alternative for some people
Science 246 , 382385 (1989)
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