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Addressing the common misconception that nicotine itself is the primary cause of tobacco-related health risks [6:45]

Y2H and GST pull-down assays showed that Pelo interacted with an E3 ubiquitin ligase, encoding a 658 amino acid protein that contained a C3HC4-type RING domain at its N-terminus (Fig

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For these regions, the side chains were stubbed in the final PDB models if no robust density was present in the EM maps