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doi: 10.1101/gr.096651.109 3 RothGAMensahGAJohnsonCOAddoloratoGAmmiratiEBaddourLMet al
We applied RTA analysis determines whether perturbation of rigidity and conformational degrees of freedom at NADH regulatory site could propagate through the protein structure (Pivotal helix, 11 and Rosenman fold) inducing the quantifiable changes in rigidity and available number of degree of freedom at a second distant site (GTP binding region), hence result in allosteric transmission
Lang CA, Naryshkin S, Schneider DL, Mills BJ, Lindeman RD
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