MAUD-T2D trial: Patients with T2D and markers of more severe AUD, comparing newer GLP-1 RAs to FDA-approved medications for AUD (MAUD: acamprosate, disulfiram, or naltrexone)
doi: 10.3945/ajcn.110.003483
In the United States, some of the medications have been approved as treatments for other conditions, including sleep apnea and reducing the risk of heart problems and kidney disease progression
Regulated Manufacturing Manufactured under FDA-regulated quality standards, ensuring consistent purity and dosing
Potential Effects to Watch For: When combining THC and GLP-1s, some users report: Stronger-than-expected highs Longer-lasting effects, especially with edibles Increased sedation or dizziness Heightened nausea in some cases (though THC can reduce nausea for others) Appetite confusion, where hunger cues feel different or muted Its worth noting that both THC and GLP-1s can independently affect appetite and digestion, so their combination may feel unusual at first