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The buildup of fat tissue can happen anywhere that insulin is given
It stimulates the pituitary gland to release growth hormone (GH), and GH itself has a mild, transient diabetogenic effect, meaning it can temporarily raise blood sugar and decrease insulin sensitivity
Research from PubMed Central shows that changes in fluid balance can play a part in initial weight shifts for those using GLP-1 medications
This suggests that the chemical modifications enhancing their stability may simultaneously limit their access to central GLP-1Rs
Wegovy is typically recommended to be used in combination with lifestyle changes like a reduced-calorie diet and exercise
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