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By comparing the gene expression profiles of the skin microbiota in acne patients with the profiles from healthy individuals, the vitamin B 12 biosynthesis pathway in the skin bacterium Propionibacterium acnes turned out to be significantly down-regulated in acne patients
2018 Aug 1;39(4):489-517
Patients should also avoid assuming that more therapies are always better
Hormonal considerations, pregnancy planning, and potentially different response profiles warrant attention
For subcutaneous injection, pinch the skin to create a fold, insert the needle at a 45-90 degree angle, and inject slowly
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