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1c,d) and was previously suggested as a candidate for a potential activator site, first, because its positive charge might stabilize or bind GSH as GS , and, second, because of its evolutionary conserved position that is equivalent to the GSH-interacting catalytic residue of glutathione transferases 3

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Frye received grant support from Assurex Health, Baszucki Group, Myriad, Mayo Foundation and BD2, received CME travel and honoraria from Carnot Laboratories and American Physician Institute and has Financial Interest/Stock ownership/Royalties from Chymia LLC