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EXAMPLE 15: EFFECT OF THE MOLAR SUBSTITUTION DEGREE OF HP-B-CD ON THE PHYSICAL AND CHEMICAL STABILITY OF CAGRILINTIDE AND SEMAGLUTIDE COFORMULATIONS This example shows the effect of the molar substitution of HP-B-CD on the formation of sub-visible particles, HMWP level and chemical purity of semaglutide in otherwise identical, citrate-buffered cagrilintide and semaglutide co-formulations

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21 Since the mitochondrion is associated with multifarious diseases and its a pivotal role in cellular physiological processes, it is foreseeable that mitochondria-targeted drug delivery will emerge as a hotspot in biomedical research

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Subcellular distribution of superoxide dismutases (SOD) in rat liver: Cu,Zn-SOD in mitochondria

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Dobutamine is a synthetic, direct-acting catecholamine that primarily stimulates -adrenergic receptors to enhance myocardial contractility and increase cardiac output

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