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5.4.2 Effects on liver Despite the lack of expression of GIPR (41, 191) and GLP-1R (192, 193) in hepatocytes, both GIP and GLP-1 have indirect effects on hepatic lipid and glucose metabolism (194)
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Key Features 99% Purity (HPLC/MS Verified) Consistent lots for reproducible results Melanocortin Agonist MC1R/MC4R engagement for pigmentation and appetite/energy signaling models Photobiology Focus Supports assays of melanocyte cAMP signaling and UV-response endpoints Protocol Friendly Lyophilized, research-grade format for precise dosing and method development GMP-Compliant, USA-Made Batch-to-batch reliability COA Included Full lot documentation Mechanistic Overview (Research Context) Melanotan II is a cyclic heptapeptide analogue of -melanocyte-stimulating hormone (-MSH) that activates melanocortin receptors : MC1R (Pigmentation Biology): Increases cAMP in melanocytes interrogate pathways for melanin synthesis , melanosome transport , and DNA-damage response models
10.1038/s41522-024-00477-w 51 LebherzC.SchlieperG.MollmannJ.KahlesF.SchwarzM.BrunsingJ.et al (2017)
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