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Different clinical symptoms reported in individual patients with 5-oxoprolinase deficiency are renal stone formation, enterocolitis, mental retardation, neonatal hypoglycemia, microcytic anemia and microcephaly [4045]
Front Endocrinol (Lausanne) (2021) 12:129
Molecules that fail the framework should be directed toward the alternative routes discussed in Section 8 or the device-mediated approaches discussed in Section 9, rather than being abandoned entirely
Vitamin B12 toxicity is extremely rare because excess amounts are excreted through urine
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