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Berberine may affect gut bacteria and digestion to increase peptides associated with appetite (including GLP-1), and regulate genes and blood sugar production from the liver

The third and fourth groups were co-administered DEX with SPAE at 400 mg/kg and 800 mg/kg body weight/day orally for the same period

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This fragment retains the lipolytic activity of full-length GH without its growth-promoting, IGF-1-elevating, or diabetogenic effects, making it a targeted tool for lipid metabolism research

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