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During the initial weeks of semaglutide therapy and during dose escalations, when gastrointestinal side effects are most pronounced, abstaining from alcohol is advisable

Aberrant methylation changes are also known to alter the structure and function of DNA and histones during cancer development (39)

Previously, SHMT2 expression has been shown to be inversely associated with tumor-infiltrating lymphocytes in the tumor microenvironment of patients with lung adenocarcinoma, using TIMER and TISIDB online databases [73, 74]

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