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GLP-1 exerts its effects through the GLP-1 receptor, which is found in various tissues, including the brain, pancreas, stomach, heart, kidneys, and adipose tissue [14, 15]
Retatrutide is the heavyweight, a triple agonist that recruits the GLP-1, GIP, and glucagon pathways in a single molecule
The cysteine-rich and glycosylated regions of DPP-4 carry out the non-enzymatic functions, involved in cell signaling, immune regulation, inflammation, and tissue remodeling (Zhong et al., 2013)
Tambin es importante consultar con un profesional de la salud en caso de condiciones mdicas preexistentes o uso de medicamentos
Arch Intern Med 170(3):256261
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