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Comparison: Tirzepatide vs Other GLP-1 Agonists and Palpitation Risk Key Takeaways Tirzepatide heart palpitations occur in 25% of patients and are caused by vagal tone modulation, fluid volume reduction, and electrolyte shifts

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Before injection, that powder must be dissolved into a liquid carrier and bacteriostatic water is the standard choice because the 0.9% benzyl alcohol in it prevents microbial contamination during the multi-week dosing period

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