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10.3389/fphar.2020.598555 100 WangH.AnP.XieE.WuQ.FangX.GaoH.et al (2017)
Key limitations of the existing evidence include: Small sample sizes in many studies Heterogeneous patient populations Variable dosing regimens (typically 35 grams daily) Short follow-up periods (often 4-12 weeks) Inconsistent outcome measures Potential publication bias favouring positive results Some studies have investigated combination approaches
Int Dent J 2002;52 Suppl 3:2016
Glutathione binds to the active site of tyrosinase, effectively blocking the enzyme's ability to catalyze the conversion of L-DOPA into melanin precursors
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Experimental research is an earlier stage
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