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Primary hepatocytes from mice lacking cysteine dioxygenase show increased cysteine concentrations and higher rates of metabolism of cysteine to hydrogen sulfide and thiosulfate
Perhaps most significantly, not a single serious adverse event was attributed to AOD-9604 administration across the entire trial program
Headache, dizziness, nausea and temporary injection-site reactions are also reported
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ALT levels significantly decreased following treatment with glutathione for 4 months
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