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Boursier J, Mueller O, Barret M, Machado M, Fizanne L, Araujo-Perez F, et al

Some individuals report increased nausea, headaches, or skin irritation when using medication that has begun to break down

Anticoagulants (Blood Thinners) If you take blood-thinning medications like warfarin, changes in how your body absorbs nutrients or medications could affect your INR levels (a measure of blood clotting)

Poor sleep increases appetite hormones (ghrelin), decreases satiety hormones (leptin), increases insulin resistance, and promotes fat storage

One potential downside to the Mediterranean keto diet is the keto flu, which some keto eaters experience as their body adjusts to ketosis