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However, if semaglutide unmasked a pre-existing GERD tendency, some degree of reflux may persist

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Because of this necessary repair work, individuals with extreme insulin resistance may need to reach the 1.0 mg therapeutic dose or higher before seeing structural weight loss on the scale

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The same mechanism that suppresses appetite, delayed gastric emptying and reduced food intake signaling, also causes the nausea, fullness, and digestive changes that patients report most frequently