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Older people sleep shorter hours and spend more time in the lighter stages of sleep than in deep sleep which better rejuvenates the body

Acknowledgements This paper was funded by grants from the National Natural Science Foundation of China (82070588, 82370577), National Key R&D Program of China (2023YFA1800801)

Media with no serum enabled stable co-cultures of iPSC-derived microglia and brain endothelial cells which respond appropriately to inflammatory stimuli, such as lipopolysaccharide (Bull et al., Induced Pluripotent Stem Cells Induced pluripotent stem cells have been used in multiple configurations: static transwell mono- or co-cultures (Stebbins et al., 2019) and monoculture microfluidic models (Faley et al., 2019), co-culture with cell lines (Park et al., 2019) or with iPSC-derived neuron or pericyte (Jamieson et al., 2019

It is a dual-agonist, meaning it mimics two different hormones: GLP-1 and GIP (glucose-dependent insulinotropic polypeptide)