The n=16 insomnia trial measured sleep efficiency and sleep latency, not muscle soreness, creatine kinase, HRV, strength recovery, or training adaptation [4]
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Conflating them produces wildly inconsistent expectations
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Data from pregnancy registries indicate infants exposed to topiramate during pregnancy have an increased risk for cleft lip and/or cleft palate and for being small for gestational age (SGA), defined as a birth weight below the tenth percentile