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The potential for altered food reward processing may benefit patients with binge eating patterns or food addiction-like behaviors, though GLP-1 medications lack specific FDA approval for eating disorders

In Phase 2 trials (the TRIUMPH-2 study involving 338 participants over 48 weeks), the 12 mg dose of Retatrutide produced an average weight loss of 24.2%

Follow-up appointments and healthcare team support help maintain the results

Common side effects of sitagliptin include: Diarrhea Headache Nausea Sore throat Stuffy or runny nose Swelling of hands or legs Upper respiratory infection Serious sitagliptin side effects include: Allergic reactions (hives, difficulty breathing or swelling of the lips, face, tongue or throat) Heart failure (rapid increase in weight, shortness of breath or swelling of the feet) Hypoglycemia (low blood sugar) Necrotizing pancreatitis (a complication of acute pancreatitis that causes tissue death) Acute pancreatitis (inflammation in the pancreas, causing abdominal pain) Severe joint pain Severe skin reaction (rash, blistering or peeling, burning eyes or facial swelling) Increased blood glucose, pancreatitis, pancreatic cancer and gastrointestinal disorders (vomiting, diarrhea and nausea) were the most commonly reported side effects of Januvia and Janumet to the FDAs Adverse Event Reporting System (FAERS)

List prices hover around $1,000 per prefilled pen that contains four weekly doses if not covered by your insurance plan, for example