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Neuron 96 , 709711 (2017)
The active compound is tirzepatide, a synthetic peptide that acts as a dual agonist at both the glucose-dependent insulinotropic polypeptide receptor (GIPR) and the glucagon-like peptide-1 receptor (GLP-1R)
lancet 360 , 13691374 (2002)
Its signaling cascade is centered around human Caspase-1, Caspase-4, and Caspase-5, or murine Caspase-11 (44)
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