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HGF and c-Met signaling are implicated in tumor cell proliferation, motility, and metastasis in hepatocellular, gastric, and non-small-cell lung cancers

The main enzymes involved in enzymatic reactions are uncoupled endothelial nitric oxide synthase (eNOS), NADPH oxidase (NOX), xanthine oxidase (XO), arachidonic acid (ARA), peroxidase, and metabolic enzymes such the cytochrome P450 system, cyclooxygenase, and lipoxygenase