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Contact your GP or pharmacist before taking cold and flu remedies alongside Wegovy if you have any of the following: Pre-existing medical conditions : Particularly cardiovascular disease, uncontrolled hypertension, diabetes, kidney or liver problems, or thyroid disorders Multiple medications : If you take several prescription medications, the cumulative interaction risk increases Previous adverse reactions : Any history of unusual responses to cold medications or GLP-1 receptor agonists Pregnancy or breastfeeding : Both Wegovy and many cold remedies require careful consideration in these circumstances Seek urgent medical attention if you experience any of the following whilst taking Wegovy and cold medications: Severe or persistent vomiting : Particularly if you cannot keep down fluids for more than 24 hours, as this increases the risk of dehydration and may indicate pancreatitis (a rare but serious side effect of GLP-1 receptor agonists) [2] [3] Severe abdominal pain : Especially if accompanied by nausea, vomiting, or fever Signs of allergic reaction : Rash, swelling of the face or throat, difficulty breathing, or rapid heartbeat Changes in vision : Blurred vision or other visual disturbances Symptoms of hypoglycaemia : If you also take diabetes medications, watch for shakiness, confusion, sweating, or rapid heartbeat Right upper abdominal pain, fever, or yellowing of the skin/eyes : These may indicate gallbladder problems, which can occur with GLP-1 receptor agonists [2] [3] Reduced urine output, dizziness, or confusion : These may indicate dehydration or acute kidney injury, especially if you're experiencing prolonged vomiting or diarrhoea Routine consultation with your pharmacist is advisable when selecting any over-the-counter medication whilst on Wegovy