Research progress on hepatotoxicity mechanism of polygonum multiflorum and its main components
Despite the accumulating evidence around pathways engaged by the GLP-1R and other GPCRs in target tissues, there is still substantial uncertainty about the precise molecular mechanisms involved, particularly with regards to the spatiotemporal organisation of their signalling and their presence in spatially restricted subcellular (or even suborganelle) signalling hubs or nanodomains 61
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J Biol Chem 281:1742017431 Michelet F, Gueguen R, Leroy P, Wellman M, Nicolas A, Siest G (1995) Blood and plasma glutathione measured in healthy subjects by HPLC: relation to sex, aging, biological variables, and life habits