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Vitamin B12 is required for the catabolism of fats and proteins, processes pertinent to weight management

There are three ways you can administer shots: subcutaneously (known also as SQ, meaning under the skin), intramuscularly (or IM) and intravenously (known as IV)

While B-12 is commonly found in various foods, some individuals may have difficulty absorbing it efficiently through the digestive system

Additionally, the relatively small number of cases might have introduced a selection bias

The mechanism is generally telogen effluvium driven by rapid weight loss rather than a direct effect of tirzepatide, similar to what is seen after bariatric surgery or any aggressive caloric deficit