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Treatments with a family of lipid-lowering drugs known as fibrates (e.g., fenofibrate, bezofibrate) have been associated with an increased excretion of betaine in the urine and a rise in homocysteine concentration in the blood of patients with diabetes mellitus or metabolic syndrome (125, 126)
[PMID: 16098782] PubMed record related to this compound for laboratory literature review
However, at partial or subtherapeutic doses, patients may feel partial benefits, such as mild appetite suppression and small changes in blood sugar levels and weight loss
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Overall, that equated to a tiny decrease in density and no clear or statistically significant evidence of real bone loss
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