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Patients were instructed to use high dose vitamin B12 nasal drops (5,000 mcg one nasal drop in each nostril, twice per week)

However, one possible explanation is the differences in the causes of liver cirrhosis and in the functional reserve capacities in patients (43,44)

GPX4-independent pathways, including FSP1/CoQ10, DHODH, and GCH1/BH4, all contribute significantly [56,60-62] (Figure 1)

Severe gastrointestinal disease such as gastroparesis or inflammatory bowel disease can be worsened by the slowed stomach emptying these drugs cause