fda glp-1 compounding crackdown september 2025 is short-sighted on GLP-1s FDA issued 25 warning letters

Sima AA, Calvani M, Mehra M, et al

Possible reasons for bowel prep to work slower than expected include: Constipation before taking prep solution: Constipation is when someone experiences difficulty passing bowel movements, and chronic constipation can slow bowel function, impacting when prep solutions work

2g Sugars

Or a seasoned biohacker

This finding has direct implications for research protocol design: most published and structured study designs incorporate a rest period following the active phase to allow receptor sensitivity to normalize before any subsequent research cycle, rather than using continuous, uninterrupted administration