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Improved insulin sensitivity: The drug helps the body metabolize glucose more efficiently, reducing the risk of developing insulin resistance and type 2 diabetes

Slowing gastric emptying and enhancing satiety signals help create a natural reduction in caloric intake

Unlike FDA-approved medications, compounded drugs are not evaluated for safety, effectiveness, or quality

Longo et al., 2025)

Future Directions: Research is expanding beyond weight loss to evaluate CagriSema's effects on cardiometabolic complications (cardiovascular disease, NASH, sleep apnea, HFpEF), special populations (adolescents, diverse ethnic groups), and quality of life outcomes