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NNMT normally burns through NAD+ precursors as a kind of metabolic "bleed." Block the bleed, and MOTS-C's expanded mitochondrial activity has more substrate to work with
Some patients experience intolerable GI side effects or cant use GLP-1 drugs due to medical contraindications
Guided Administration Plan: Structured scheduling based on medical evaluation
There are practical reasons too: B can be unstable if mixed with certain other vitamins in solution, and dosing schedules for B deficiency (pernicious anemia, for instance) may differ
Chronic treatment should be done with an oral preparation in patients with normal intestinal absorption
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